Rotenone - an overview

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Rotenone

 Rotenone is a naturally occurring compound found in the roots of several plant species and has been extensively used as an insecticide and to kill fish.

 1. Rotenone, an organic pesticide that interrupts complex I of the electron transport chain, also elicits mitochondrial dysfunction and ultimately cell loss in the nigrostriatal pathway.

 2. Rotenone is one of the naturally occurring insecticides present in a number of plants of Derris, Lonchocarpus, Tephrosia, and Mundulea species. 

 2.1. Rotenone occurs naturally in roots and stems of several tropical and subtropical plant species especially those belonging to the genus Lonchocarpus or Derris.

 3. It has a molecular formula of C23H22O6 and a molecular weight of 394.42. 

4. Rotenone is used worldwide because it has broad spectrum insecticidal, acaricidal, and other pesticidal properties. Its formulations include crystalline preparations (about 95%), emulsifiable solutions (about 50%), and dust (0.75%). 


 Topic - Biology, Biotechnology, Research, GATE, NTA CSIR - NET exam

source: https://www.sciencedirect.com/topics/neuroscience/rotenone

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