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Q. 001: Histidine is the active site residue in a large number of enzymes because -  

a. The pKa of the imidazole moiety in the histidine is 6.5 

b. It forms salt bridges with lysine residue in the substrate 

c. It forms hydrogen bonds with the residues in the substrate 

d. It is a good buffering agent at the physiological pH 


Ans: d

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